Automated deconvolution of
biomolecule mass spectra to determine molecular mass: applicable to proteins,
peptides, oligonucleotides, etc. ProMass features the following:
Automated deconvolution of
biomolecule mass spectra to determine molecular mass: applicable to proteins,
peptides, oligonucleotides, etc.
Integrated with Finnigan Xcalibur
data system
Artifact-free deconvolution using
proprietary ZNova algorithm, no manual intervention required to remove artifact
peaks
Applicable to high and low charge
state spectra (e.g., works on peptides as well as proteins)
Automatically apply spectral
smoothing and baseline removal prior to deconvolution
Processing of LC/MS peaks directed
by Xcalibur processing method. Data may be processed
on the N biggest chromatographic peaks, all peaks above a relative intensity
threshold, etc. Automatic background
subraction
is also
supported.
Process data
from a spectrum on the Windows clipboard
Automated web-based reporting,
including summary report, chromatograms (UV and MS), raw, and deconvoluted mass
spectra
Automatically
calculate expected masses of target oligonucleotides and polypeptides
Color-coded results display
and ProMass Browser summary
report allow for rapid visualization of your
results, included integrated sample plate viewer
Automatically search for multiple
target
masses and report results in color-coded web-based summary
Optionally produces Excel-based summary for
all samples processed
Chromatograms automatically labeled
with base peak deconvoluted masses
ESI spectra automatically labeled
with charge states of most abundant components
Peak lists and log files
automatically generated for each deconvoluted spectrum including information
about mass, standard deviation, score, and deconvolution parameters
Process either profile or centroid
data. Optionally produce centroided output for either data type.
Direct output to folders that are
specified explicitly, based upon the input filename, based upon the date, or
based on the location of acquired data
Includes GUI
for parameter setup, sequence setup, processing method validation, and interactive viewing
of deconvoluted spectra in ProMass DecView
Web-based report can be customized
with your own corporate logo
Custom reporting options available
upon request
Can be combined with trap/wash/elute
sample cleanup for totally automated sample analysis
The ZNova core algorithm is fully
scriptable through its command line interface, allowing you to create your own
applications if desired (e.g., a CGI version of ZNova).
The ZNova core algorithm has been designed
to be easily portable among the various computer platforms (PC, Mac, UNIX,
Linux, etc.). If you are interested in custom development or deployment on
another data system, please feel free to contact us.