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ZNova Speed Benchmarks comparing ZNova 1.2 (new) algorithm speed vs. ZNova 1.1 (old)

Biomolecule / description

Deconvolution Range

ZNova Iteration Time (sec) - old

ZNova Iteration Time (sec) - new

ZNova Speed Increase

Overall Processing Time (sec) - old

Overall Processing Time (sec) - new

Overall Speed Increase

myoglobin

0.5-20 kD

2.5

0.94

2.7

18.2

13.4

1.4

Heavy chain / light chain IgG mix

10-65 kD

3.4

4.4

32.9

14.4

2.3

40 kD protein, very noisy data

25-100 kD

233.9

24.7

9.5

254.9

34.9

7.3

tryptic peptide

0.5-5 kD

0.17

0.13

1.3

7.3

1.0

Average ZNova Speed Increase

4.5

Average Overall Speed Increase

3.0

Notes:

ZNova iteration time includes the time required to perform the main ZNova deconvolution calculations, not including baseline removal, smoothing, and report generation.

Overall processing time includes the time required to process the entire spectrum, including pre-processing, deconvolution, and report generation.

Test system: Pentium III 750 MHz Dell C600 laptop with Windows 2000 and 256 MB RAM

Example ZNova 1.2 Deconvolution of heavy chain / light chain IgG mixture